Stimulation of retinoic acid of synthesis and turnover of basement membrane in mouse embryonal carcinoma-derived endoderm cells.

@article{Salomon1982StimulationOR,
  title={Stimulation of retinoic acid of synthesis and turnover of basement membrane in mouse embryonal carcinoma-derived endoderm cells.},
  author={David S. Salomon and Lance A. Liotta and Stephen I. Rennard and Jean Michel Foidart and V Terranova and Mina Yaar},
  journal={Collagen and related research},
  year={1982},
  volume={2 2},
  pages={93-110}
}
The effect of retinoic acid on the synthesis and degradation of basement membrane components by endoderm cells derived from mouse embryonal carcinoma (EC) cells was studied in a serum-free, defined medium. By immunofluorescence these cells accumulate type IV collagen, laminin, and fibronectin after growth in media containing epidermal growth factor (EGF), fibroblast growth factor (FGF), insulin, transferrin, and Pedersen fetuin. Collagen accounted for 2 to 4% of the newly synthesized proteins… CONTINUE READING