Stimulation of proteoglycan production by glucosamine sulfate in chondrocytes isolated from human osteoarthritic articular cartilage in vitro.

@article{Bassleer1998StimulationOP,
  title={Stimulation of proteoglycan production by glucosamine sulfate in chondrocytes isolated from human osteoarthritic articular cartilage in vitro.},
  author={C T Bassleer and Luca Carlo Vittorio Rovati and Paul Franchimont},
  journal={Osteoarthritis and cartilage},
  year={1998},
  volume={6 6},
  pages={427-34}
}
OBJECTIVE This study investigated the in-vitro effects of a crystalline glucosamine sulfate (GS) preparation on DNA synthesis and on proteoglycan (PG) and type II collagen (coll II) production by human articular chondrocytes isolated from human osteoarthritic articular cartilage in a 3-dimensional culture system for 4, 8, and 12 days. MATERIALS AND METHODS Human articular chondrocytes from osteoarthritic femoral heads were isolated from their matrix by collagenase digestion and then cultured… CONTINUE READING

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