Stimulation of protein tyrosine phosphorylation by a progesterone receptor on the cell surface of human sperm.

  title={Stimulation of protein tyrosine phosphorylation by a progesterone receptor on the cell surface of human sperm.},
  author={Jan Tesarik and Jiř{\'i} Moos and Carmen Mendoza},
  volume={133 1},
Mature human sperm initiate a rapid Ca2+ influx and the acrosomal exocytosis in response to progesterone. Recent evidence indicates that both events can be induced by antibody-mediated cross-linking of a sperm surface progesterone receptor. In many other systems in which signal is generated by receptor cross-linking, protein phosphorylation on tyrosine residues is involved in the signal transduction across the plasma membrane. In this study we examined whether tyrosine phosphorylation is… 

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  • D. Cadena, G. Gill
  • Biology
    FASEB journal : official publication of the Federation of American Societies for Experimental Biology
  • 1992
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