Stimulation of protein (collagen) synthesis in sponge cells by a cardiac myotrophin-related molecule from Suberites domuncula.

@article{Schrder2000StimulationOP,
  title={Stimulation of protein (collagen) synthesis in sponge cells by a cardiac myotrophin-related molecule from Suberites domuncula.},
  author={Heinz C. Schr{\"o}der and Anatoli Krasko and Renato Batel and Alexander Skorokhod and Sabine Pahler and M. Kruse and Isabel M. M{\"u}ller and Werner E. G. M{\"u}ller},
  journal={FASEB journal : official publication of the Federation of American Societies for Experimental Biology},
  year={2000},
  volume={14 13},
  pages={2022-31}
}
The body wall of sponges (Porifera), the lowest metazoan phylum, is formed by two epithelial cell layers of exopinacocytes and endopinacocytes, both of which are associated with collagen fibrils. Here we show that a myotrophin-like polypeptide from the sponge Suberites domuncula causes the expression of collagen in cells from the same sponge in vitro. The cDNA of the sponge myotrophin was isolated; the potential open reading frame of 360 nt encodes a 120 aa long protein (Mr of 12,837). The… CONTINUE READING

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Establishment of a primary cell culture from a sponge: primmorphs from Suberites domuncula

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