Stimulation of prostaglandin formation by vasoactive mediators in cultured human endothelial cells.

@article{AlhencGlas1982StimulationOP,
  title={Stimulation of prostaglandin formation by vasoactive mediators in cultured human endothelial cells.},
  author={François Alhenc-G{\'e}las and Simon Tsai and Karleen S. Callahan and William Campbell and Alice. R. Johnson},
  journal={Prostaglandins},
  year={1982},
  volume={24 5},
  pages={
          723-42
        }
}
Human endothelial cells in culture synthesize prostaglandins and release these products into the culture medium. The major products of arachidonic acid metabolism were identified by high pressure liquid chromatography or thin layer chromatography, and release of prostaglandins was measured by radioimmunoassays. Addition of histamine or bradykinin enhanced release of prostaglandins in both arterial and venous endothelial cells. Other vasoactive compounds including angiotensin II, vasopressin… CONTINUE READING
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