Stimulation of pituitary gonadotropin release does not require internalization of gonadotropin-releasing hormone.

@article{Conn1981StimulationOP,
  title={Stimulation of pituitary gonadotropin release does not require internalization of gonadotropin-releasing hormone.},
  author={P. Michael Conn and R. G. Smith and Deloris C. Rogers},
  journal={The Journal of biological chemistry},
  year={1981},
  volume={256 3},
  pages={1098-100}
}
Binding of gonadotropin-releasing hormone (GnRH, pyro-Glu1-His2-Trp3-Ser4-Tyr5-Gly6-Leu7-Arg8-Pro9-Gly-NH210) to its plasma membrane receptor is the first step leading to the release of pituitary luteinizing hormone. As in the case of other plasma membrane receptors, patching, capping, and internalization of this hormone-receptor complex occurs rapidly following exposure of cultured pituitary cells to physiological levels of releasing hormone. In the present study we sought to determine whether… CONTINUE READING

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DetergentsNo subtypeSoap
Exposure of the product to proteases , soaps , detergents , solvents , chaotropic agents , or cell cultures resulted in dissociation of < 0.28% of biologically active releasing hormone .
DetergentsNo subtypeSoap
Exposure of the product to proteases , soaps , detergents , solvents , chaotropic agents , or cell cultures resulted in dissociation of < 0.28% of biologically active releasing hormone .
SoapNo subtypeDetergents
Exposure of the product to proteases , soaps , detergents , solvents , chaotropic agents , or cell cultures resulted in dissociation of < 0.28% of biologically active releasing hormone .
Stimulation of pituitary gonadotropin release does not require internalization of gonadotropin - releasing hormone .
Stimulation of pituitary gonadotropin release does not require internalization of gonadotropin - releasing hormone .
SoapNo subtypeDetergents
Exposure of the product to proteases , soaps , detergents , solvents , chaotropic agents , or cell cultures resulted in dissociation of < 0.28% of biologically active releasing hormone .
SoapNo subtypeDetergents
Exposure of the product to proteases , soaps , detergents , solvents , chaotropic agents , or cell cultures resulted in dissociation of < 0.28% of biologically active releasing hormone .
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