Stimulation of minor salivary glands by intraoral treatment with the cholinesterase inhibitor physostigmine in man.

Abstract

A large number of the population, especially the elderly, suffers from dry mouth. The aim of the present investigation was to stimulate the minor salivary glands by the topical application of the cholinesterase inhibitor physostigmine. In eight healthy subjects. 100 microl of the substance, in the concentration interval 2-8 mg/ml, was applied locally to the… (More)

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