Stimulation of migration and wound repair of guinea-pig airway epithelial cells in response to epidermal growth factor.

@article{Kim1998StimulationOM,
  title={Stimulation of migration and wound repair of guinea-pig airway epithelial cells in response to epidermal growth factor.},
  author={Jaime Kim and Valerie S McKinnis and Arthur Nawrocki and Steven R White},
  journal={American journal of respiratory cell and molecular biology},
  year={1998},
  volume={18 1},
  pages={66-74}
}
Repair of the airway epithelium after injury involves cell proliferation, migration, and spreading into the injury site. The growth factor, epidermal growth factor (EGF), elicits proliferation of many epithelial cell types in vitro and in vivo, including airways epithelium. However, its effects on cell migration and spreading are less clear. We studied the effects of EGF on guinea-pig tracheal epithelial cell (GPTEC) chemotaxis and migration during wound repair. Primary GPTEC were allowed to… CONTINUE READING