Stimulation of macrophages by Bacillus firmus: production of nitric oxide and cytokines.

@article{Zdek1998StimulationOM,
  title={Stimulation of macrophages by Bacillus firmus: production of nitric oxide and cytokines.},
  author={Zdeněk Z{\'i}dek and Ludmila Tu{\vc}kov{\'a} and Michal M{\'a}ra and Rita Barot-Ciorbaru and Ludmila Proke{\vs}ov{\'a} and Helena Tlaskalova-Hogenova},
  journal={International journal of immunopharmacology},
  year={1998},
  volume={20 7},
  pages={359-68}
}
Immunostimulatory properties of gram-positive Bacillus firmus were investigated under in vitro conditions using murine peritoneal macrophages. B. firmus stimulated in a concentration and time dependent manner the secretion of tumour necrosis factor-alpha (TNF-alpha) and interleukin-10 (IL-10), but it had no influence upon interferon-gamma (IFN-gamma) and interleukin-2 (IL-2) production. It also substantially augmented production of nitric oxide (NO) induced by exogenous IFN-gamma. Inhibitory… CONTINUE READING