Stimulation of lung innate immunity protects against lethal pneumococcal pneumonia in mice.

Abstract

RATIONALE The lungs are a common site of serious infection in both healthy and immunocompromised subjects, and the most likely route of delivery of a bioterror agent. Since the airway epithelium shows great structural plasticity in response to inflammatory stimuli, we hypothesized it might also show functional plasticity. OBJECTIVES To test the… (More)
DOI: 10.1164/rccm.200607-1038OC

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