Stimulation of interleukin 6-like B-cell differentiation factor production in human adherent synovial cells by recombinant interleukin 1.

@article{Harigai1989StimulationOI,
  title={Stimulation of interleukin 6-like B-cell differentiation factor production in human adherent synovial cells by recombinant interleukin 1.},
  author={Masayoshi Harigai and Masako Hara and K Norioka and Akira Kitani and Takahisa Hirose and Katsuya Suzuki and Masanobu Kawakami and K Masuda and Masayuki Shinmei and Masami Kawagoe},
  journal={Scandinavian journal of immunology},
  year={1989},
  volume={29 3},
  pages={289-97}
}
Abnormal production of immunoglobulin in the joint space is frequently observed in patients with rheumatoid arthritis (RA). We have previously demonstrated that adherent synovial cells (ASC) from patients with RA are involved in B-cell differentiation by their spontaneous production of B-cell differentiation factor (BCDF). The regulation of the production… CONTINUE READING