Stimulation of inositol trisphosphate and diacylglycerol production in renal tubular cells by parathyroid hormone.

@article{Hruska1987StimulationOI,
  title={Stimulation of inositol trisphosphate and diacylglycerol production in renal tubular cells by parathyroid hormone.},
  author={Keith A. Hruska and David M. Moskowitz and Pedro Esbrit and Roberto Civitelli and Simon Lemprier Westbrook and Margaret Huskey},
  journal={The Journal of clinical investigation},
  year={1987},
  volume={79 1},
  pages={
          230-9
        }
}
Parathyroid hormone (PTH) produced a dose-dependent immediate stimulation of inositol triphosphate and diacylglycerol production in the opossum kidney cell line, primary culture proximal tubular cells, and basolateral membranes from canine proximal tubular segments. The increase in inositol triphosphate production was accompanied by a minor increase in inositol phosphate and no significant increase in inositol bisphosphate production. Associated with the changes in inositol triphosphate and… CONTINUE READING
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