Stimulation of gastrin-CCKB receptor promotes migration of gastric AGS cells via multiple paracrine pathways.

@article{Noble2003StimulationOG,
  title={Stimulation of gastrin-CCKB receptor promotes migration of gastric AGS cells via multiple paracrine pathways.},
  author={Peter J M Noble and Geraint J. C. Wilde and Michael R. H. White and Steven R Pennington and Graham J. Dockray and Andrea Varr{\'o}},
  journal={American journal of physiology. Gastrointestinal and liver physiology},
  year={2003},
  volume={284 1},
  pages={G75-84}
}
Responses to G protein-coupled receptor stimulation may be mediated by paracrine factors. We have developed a coculture system to study paracrine regulation of migration of gastric epithelial (AGS) cells after stimulation of gastrin-CCK(B) receptors. In cells expressing this receptor, G-17 stimulated migration by activation of protein kinase C. However, G-17 also stimulated the migration of cells expressing green fluorescent protein, but not the receptor, when they were cocultured with receptor… CONTINUE READING
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Measurement of MAP kinase activation by flow cytometry using phospho-specific anti G83 GPCR STIMULATION OF EPITHELIAL CELL MIGRATION AJP-Gastrointest Liver Physiol

  • S Chow, H Patel, DW. Hedley
  • 2003
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