Stimulation of gastric acid secretion and intestinal motility by Vernonia amygdalina extract.

Abstract

Aqueous extract of Vernonia amygdalina infused intragastrically at a dose of 10 mg/ml to rats induced a significant increase in acid output which was reduced by, ranitidine (5 mg/kg b.w.) or atropine (1.2 microMol/kg b.w.). Moreover the extract evoked a dose-dependent contraction of the guinea pig ileum at a dose range of 0.6 mg/ml to 66 mg/ml which was… (More)

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@article{Owu2008StimulationOG, title={Stimulation of gastric acid secretion and intestinal motility by Vernonia amygdalina extract.}, author={Daniel U. Owu and E. E. Ben and Atim B. Antai and E A Ekpe and P. M. Udia}, journal={Fitoterapia}, year={2008}, volume={79 2}, pages={97-100} }