Stimulation of fat storage by prostacyclin and selective agonists of prostanoid IP receptor during the maturation phase of cultured adipocytes

@article{Khan2016StimulationOF,
  title={Stimulation of fat storage by prostacyclin and selective agonists of prostanoid IP receptor during the maturation phase of cultured adipocytes},
  author={F. Khan and Pinky Karim Syeda and M. Nartey and M. S. Rahman and M. S. Islam and Kohji Nishimura and M. Jisaka and Fumiaki Shono and K. Yokota},
  journal={Cytotechnology},
  year={2016},
  volume={68},
  pages={2417-2429}
}
  • F. Khan, Pinky Karim Syeda, +6 authors K. Yokota
  • Published 2016
  • Biology, Medicine
  • Cytotechnology
  • We have previously shown that cultured adipocytes have the ability to biosynthesize prostaglandin (PG) I2 called alternatively as prostacyclin during the maturation phase by the positive regulation of gene expression of PGI synthase and the prostanoid IP receptor. To clarify how prostacyclin regulates adipogenesis, we investigated the effects of prostacyclin and the specific agonists or antagonists for the IP receptor on the storage of fats during the maturation phase of cultured adipocytes… CONTINUE READING
    4 Citations

    References

    SHOWING 1-10 OF 50 REFERENCES
    Prostacyclin as a potent effector of adipose-cell differentiation.
    • 136
    • Highly Influential
    • PDF
    Endogenous synthesis of prostacyclin was positively regulated during the maturation phase of cultured adipocytes
    • 2
    • Highly Influential
    Regulation and role of arachidonate cascade during changes in life cycle of adipocytes
    • 36
    Autocrine control of adipose cell differentiation by prostacyclin and PGF2 alpha.
    • 60
    Prostanoid EP4 receptor is involved in suppression of 3T3-L1 adipocyte differentiation.
    • 83
    • Highly Influential
    IP receptor-dependent activation of PPARγ by stable prostacyclin analogues
    • 54
    A novel pathway of prostacyclin signaling-hanging out with nuclear receptors.
    • 148
    • PDF
    Arachidonic acid and prostacyclin signaling promote adipose tissue development: a human health concern?
    • 289
    • Highly Influential
    • PDF
    Suppression of adipogenesis program in cultured preadipocytes transfected stably with cyclooxygenase isoforms.
    • 23