Stimulation of dopamine receptors in the paraventricular nucleus of the hypothalamus of male rats induces penile erection and increases extra-cellular dopamine in the nucleus accumbens: Involvement of central oxytocin

@article{Succu2007StimulationOD,
  title={Stimulation of dopamine receptors in the paraventricular nucleus of the hypothalamus of male rats induces penile erection and increases extra-cellular dopamine in the nucleus accumbens: Involvement of central oxytocin},
  author={Salvatora Succu and Fabrizio Sanna and Tiziana Melis and Antonio Boi and Antonio Argiolas and Maria Rosaria Melis},
  journal={Neuropharmacology},
  year={2007},
  volume={52},
  pages={1034-1043}
}
Oxytocin injected into the ventral tegmental area induces penile erection and increases extracellular dopamine in the nucleus accumbens and paraventricular nucleus of the hypothalamus of male rats
TLDR
Results provide further support for the existence of a neural circuit in which dopamine and oxytocin influence both the consummatory and motivational/rewarding aspects of sexual behaviour.
Oxytocin injected into the ventral subiculum or the posteromedial cortical nucleus of the amygdala induces penile erection and increases extracellular dopamine levels in the nucleus accumbens of male rats
TLDR
Results provide evidence that the ventral subiculum and the posteromedial cortical nucleus of the amygdala participate in a neural circuit that controls not only the consummatory aspects of sexual behaviour, but also its motivational/reward aspects, confirming a key role of oxytocin and dopamine in these processes.
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References

SHOWING 1-10 OF 66 REFERENCES
Extra‐cellular dopamine increases in the paraventricular nucleus of male rats during sexual activity
TLDR
Results confirm the involvement of the paraventricular nucleus in control of erectile function and copulatory behaviour and show for the first time that dopamine neurotransmission is increased in this hypothalamic nucleus when erection occurs in physiological contexts.
Dopamine Agonists Increase Nitric Oxide Production in the Paraventricular Nucleus of the Hypothalamus: Correlation with Penile Erection and Yawning
TLDR
It is inferred that dopamine agonists induce penile erection and yawning by acting on D2 receptors that increase nitric oxide synthase activity in the cell bodies of paraventricular oxytocinergic neurons projecting to extra‐hypothalamic brain areas.
Central Mechanisms Regulating Penile Erection in Conscious Rats: The Dopaminergic Systems Related to the Proerectile Effect of Apomorphine
TLDR
The results suggest that the proerectile action of apomorphine in rats is mediated at supraspinal levels and that this effect is not mimicked by a D2 receptor agonist but associated with activation of D4 receptors.
Pharmacological profile of dopamine receptor agonists as studied by brain dialysis in behaving rats.
TLDR
Investigation of the effect of various dopamine (DA) receptor agonists on the release and metabolism of DA in two terminal dopaminergic areas in freely moving rats finds inhibition of DA release appears related to the ability of the various agonists to stimulate D-2 rather than D-1 receptors.
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