Stimulation of cyclic AMP (cAMP) accumulation in epithelial cells of human colon by plasma from children with watery diarrhea syndrome (WDS): role of vasoactive intestinal peptide (VIP).

Abstract

The effect of plasma sampled in 2 children with WDS related to ganglioneuroblastoma was tested on the cultured cell line HT 29, derived from adenocarcinoma of human colon, that was found to possess a highly sensitive (3 × 10−12 M) cAMP system specific for VIP. Results showed that: 1) plasma from children with WDS strongly stimulated cAMP accumulation in HT… (More)
DOI: 10.1203/00006450-197910000-00024

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@article{Dupont1979StimulationOC, title={Stimulation of cyclic AMP (cAMP) accumulation in epithelial cells of human colon by plasma from children with watery diarrhea syndrome (WDS): role of vasoactive intestinal peptide (VIP).}, author={Christophe Dupont and Marc Laburthe and J. - M. Besson and Gabriel Rosselin}, journal={Pediatric Research}, year={1979}, volume={13}, pages={1184-1184} }