Stimulation of colonic glycoprotein synthesis by dibutyryl cyclic AMP and theophylline.

@article{Lamont1977StimulationOC,
  title={Stimulation of colonic glycoprotein synthesis by dibutyryl cyclic AMP and theophylline.},
  author={J. Thomas Lamont and Alfredo Ventola},
  journal={Gastroenterology},
  year={1977},
  volume={72 1},
  pages={
          82-6
        }
}
The effects of dibutyryl cyclic AMP (B2cAMP) and theophylline on glyoprotein synthesis in rabbit colon were studied in mucosal organ cultures using [3H]glucosamine as a precursor. Addition of B2cAMP (1 mm) to culture medium caused a significant increase in glycoprotein synthesis after 12 and 24 hr compared with biopsies cultured in control medium. The increase in glycoprotein synthesis was observed only if the cyclic nucleotide was present continuously in the incubation medium for at least 12… Expand
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