Stimulation of cell proliferation by tumor-promoting phorbol esters and inhibition by some inhibitors of tumor promotion in suspension cultures of a human lymphoblastoid cell line


A human lymphoblastoid cell line, SCC-1, was established from the bone marrow of a patient with acute nonlymphocytic leukemia. 12-O-Tetradecanoylphorbol-13-acetate (TPA) enhanced cell proliferation of SCC-1 cells in suspension culture. A positive correlation was found between the tumor-promoting activities of several plant diterpenes and their enhancing… (More)
DOI: 10.1007/BF00399904


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