Stimulation of cell migration by overexpression of focal adhesion kinase and its association with Src and Fyn.

@article{Cary1996StimulationOC,
  title={Stimulation of cell migration by overexpression of focal adhesion kinase and its association with Src and Fyn.},
  author={Leslie A. Cary and Julia Y F Chang and Jun-Lin Guan},
  journal={Journal of cell science},
  year={1996},
  volume={109 ( Pt 7)},
  pages={1787-94}
}
Cellular interactions with the extracellular matrix proteins play important roles in a variety of biological processes. Recent studies suggest that integrin-mediated cell-matrix interaction can transduce biochemical signals across the plasma membrane to regulate cellular functions such as proliferation, differentiation and migration. These studies have implicated a critical role of focal adhesion kinase (FAK) in integrin-mediated signal transduction pathways. We report here that overexpression… CONTINUE READING
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Fibronectin/integrin interaction induces tyrosine phosphorylation of a 120-kDa protein

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