• Corpus ID: 3019735

Stimulation of cell migration by overexpression of focal adhesion kinase and its association with Src and Fyn.

  title={Stimulation of cell migration by overexpression of focal adhesion kinase and its association with Src and Fyn.},
  author={Leslie A. Cary and J F Chang and Jun-Lin Guan},
  journal={Journal of cell science},
  volume={109 ( Pt 7)},
Cellular interactions with the extracellular matrix proteins play important roles in a variety of biological processes. Recent studies suggest that integrin-mediated cell-matrix interaction can transduce biochemical signals across the plasma membrane to regulate cellular functions such as proliferation, differentiation and migration. These studies have implicated a critical role of focal adhesion kinase (FAK) in integrin-mediated signal transduction pathways. We report here that overexpression… 

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