Stimulation of catecholamine secretion from cultured chromaffin cells by an ionophore-mediated rise in intracellular sodium

Abstract

The significance of intracellular Na+ concentration in catecholamine secretion of cultured bovine adrenal chromaffin cells was investigated using the monovalent carboxylic ionophore monensin. This ionophore, which is known to mediate a one-for-one exchange of intracellular K+ for extracellular Na+, induces a slow, prolonged release of catecholamines which… (More)

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@article{Suchard1982StimulationOC, title={Stimulation of catecholamine secretion from cultured chromaffin cells by an ionophore-mediated rise in intracellular sodium}, author={S J Suchard and Francesca Lattanzio and R. W. Rubin and Berton C. Pressman}, journal={The Journal of Cell Biology}, year={1982}, volume={94}, pages={531 - 539} }