Stimulation of bone repair with ultrasound: a review of the possible mechanic effects.

@article{Padilla2014StimulationOB,
  title={Stimulation of bone repair with ultrasound: a review of the possible mechanic effects.},
  author={Fr{\'e}d{\'e}ric Padilla and Regina Puts and Laurence Vico and Kay Raum},
  journal={Ultrasonics},
  year={2014},
  volume={54 5},
  pages={1125-45}
}
In vivo and in vitro studies have demonstrated the positive role that ultrasound can play in the enhancement of fracture healing or in the reactivation of a failed healing process. We review the several options available for the use of ultrasound in this context, either to induce a direct physical effect (LIPUS, shock waves), to deliver bioactive molecules such as growth factors, or to transfect cells with osteogenic plasmids; with a main focus on LIPUS (or Low Intensity Pulsed Ultrasound) as… CONTINUE READING
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