Stimulation of Suicidal Erythrocyte Death by Tafenoquine.

  title={Stimulation of Suicidal Erythrocyte Death by Tafenoquine.},
  author={Abdulla Al Mamun Bhuyan and Rosi Bissinger and Katja Stockinger and Florian Lang},
  journal={Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology},
  volume={39 6},
BACKGROUND/AIMS The 8-aminoquinoline tafenoquine has been shown to be effective against Plasmodia, Leishmania and Trypanosoma. The substance is at least in part effective by triggering apoptosis of the parasites. Similar to apoptosis, erythrocytes may enter suicidal death or eryptosis, which is characterized by cell shrinkage and cell membrane scrambling… CONTINUE READING