Stimulation of Sertoli cell inhibin secretion by the testicular paracrine factor PModS

  title={Stimulation of Sertoli cell inhibin secretion by the testicular paracrine factor PModS},
  author={M. Skinner and R. McLachlan and W. Bremner},
  journal={Molecular and Cellular Endocrinology},
  • M. Skinner, R. McLachlan, W. Bremner
  • Published 1989
  • Biology, Medicine
  • Molecular and Cellular Endocrinology
  • The testicular paracrine factor PModS is produced by peritubular myoid cells under androgen control and modulates Sertoli cell function and differentiation. The observation that luteinizing hormone (LH) stimulates inhibin production in vivo, but has no effect on isolated Sertoli cells in vitro, suggested an indirect mode of LH action, potentially mediated by PModS. The effects of the testicular paracrine factor PModS and hormones on inhibin secretion by Sertoli cells were investigated to… CONTINUE READING
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