Stimulation of Glia Reveals Modulation of Mammalian Spinal Motor Networks by Adenosine

@inproceedings{Acton2015StimulationOG,
  title={Stimulation of Glia Reveals Modulation of Mammalian Spinal Motor Networks by Adenosine},
  author={David G Acton and Gareth Miles and Thomas H Gillingwater},
  booktitle={PloS one},
  year={2015}
}
Despite considerable evidence that glia can release modulators to influence the excitability of neighbouring neurons, the importance of gliotransmission for the operation of neural networks and in shaping behaviour remains controversial. Here we characterise the contribution of glia to the modulation of the mammalian spinal central pattern generator for locomotion, the output of which is directly relatable to a defined behaviour. Glia were stimulated by specific activation of protease-activated… CONTINUE READING
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