Stimulation of DNA synthesis in quiescent rabbit chondrocytes in culture by limited exposure to somatomedin-like growth factors.

@article{Hiraki1986StimulationOD,
  title={Stimulation of DNA synthesis in quiescent rabbit chondrocytes in culture by limited exposure to somatomedin-like growth factors.},
  author={Yuji Hiraki and Yukio Kato and Hiroyasu Inoue and Fujio Suzuki},
  journal={European journal of biochemistry},
  year={1986},
  volume={158 2},
  pages={333-7}
}
Cartilage-derived factor (CDF), extracted from fetal bovine cartilage, and multiplication-stimulating activity (MSA) stimulated DNA synthesis in quiescent rabbit costal chondrocytes in culture under serum-free conditions. As described previously, when added in the presence of fibroblast growth factor (FGF) or epidermal growth factor (EGF) a somatomedin-like growth factor, CDF or MSA, synergistically stimulated DNA synthesis in the cultured chondrocytes. The present study showed that exposure of… CONTINUE READING