Stimulation of DNA and RNA synthesis in cultured rabbit cardiac fibroblasts by angiotensin IV.

@article{WANG1995StimulationOD,
  title={Stimulation of DNA and RNA synthesis in cultured rabbit cardiac fibroblasts by angiotensin IV.},
  author={L-D. WANG and Marc Eberhard and P. Erne},
  journal={Clinical science},
  year={1995},
  volume={88 5},
  pages={557-62}
}
1. Although angiotensin II (ANG II) has been identified as a key factor in the development of cardiac hypertrophy and remodelling, the role of its degradation fragment ANG II (3-8), angiotensin IV (ANG IV), is unknown. The presence of ANG IV in the blood circulation as well as the identification of ANG IV receptors in the heart and other organs indicates that ANG IV may act as a peptide hormone. 2. ANG IV receptors were characterized by binding of 125I-ANG IV to membranes of cultured rabbit… CONTINUE READING

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