Stimulation of Chinese hamster ovary cells expressing human thyrotropin receptors by serum human chorionic gonadotropin of patients with hydatidiform mole.

@article{Hosoi1999StimulationOC,
  title={Stimulation of Chinese hamster ovary cells expressing human thyrotropin receptors by serum human chorionic gonadotropin of patients with hydatidiform mole.},
  author={Yoshio Hosoi and Masami Murakami and Takashi Minegishi and Hiromitsu Okano and Yoshito Ibuki and Takashi Takeuchi and Masatomo Mori},
  journal={Thyroid : official journal of the American Thyroid Association},
  year={1999},
  volume={9 12},
  pages={1205-10}
}
We evaluated the stimulation of Chinese hamster ovary cells expressing human thyrotropin receptors (CHO-hTSHR cell) by sera of five patients with hydatidiform mole before and after the evacuation of the mole, and compared the results with serum human chorionic gonadotropin (hCG) concentrations and serum free thyroid hormones in these patients. Significantly increased CHO-hTSHR cell stimulating activities were observed in sera from untreated patients, and the activity decreased promptly after… CONTINUE READING