Stimulation of Bordetella pertussis adenylate cyclase toxin intoxication by its hemolysin domain.

Abstract

The internalization of the N-terminal catalytic domain of Bordetella pertussis adenylate cyclase toxin (ACT) across the cytoplasmic membrane has been considered to occur independently from protein-protein interactions which can lead to oligomerization required for hemolytic activity by its C-terminal hemolysin domain. Here we report that when added in… (More)

Topics

3 Figures and Tables

Cite this paper

@article{Iwaki2000StimulationOB, title={Stimulation of Bordetella pertussis adenylate cyclase toxin intoxication by its hemolysin domain.}, author={Masaaki Iwaki and Kazunari Kamachi and Toshifumi Konda}, journal={Infection and immunity}, year={2000}, volume={68 6}, pages={3727-30} }