Stimulation of AMP-activated protein kinase (AMPK) is associated with enhancement of Glut1-mediated glucose transport.

@article{Abbud2000StimulationOA,
  title={Stimulation of AMP-activated protein kinase (AMPK) is associated with enhancement of Glut1-mediated glucose transport.},
  author={W Abbud and Susan Amy Habinowski and J Z Zhang and Jane Kendrew and F S Elkairi and Bruce E. Kemp and Lee Alan Witters and Faramarz Ismail-Beigi},
  journal={Archives of biochemistry and biophysics},
  year={2000},
  volume={380 2},
  pages={347-52}
}
In cells expressing only the Glut1 isoform of glucose transporters, we have shown that glucose transport is markedly stimulated in response to hypoxia or inhibition of oxidative phosphorylation, conditions that would be expected to cause a stimulation of AMP-activated protein kinase (AMPK) activity. In the present study we tested the hypothesis that the… CONTINUE READING