Stimulation-induced gene expression in Ramos B-cells

  title={Stimulation-induced gene expression in Ramos B-cells},
  author={Juha Ollila and Mauno Vihinen},
  journal={Genes and Immunity},
The development of adaptive immunity and responses to foreign molecules and organisms relies on the highly regulated production of hundreds of proteins. B-cell maturation, from committed progenitors to terminally differentiated plasma cells, is a multistep process that requires the ordered expression of a large number of genes. We studied anti-IgM-stimulated Ramos cells to explore genome-wide expression patterns in differentiating human B-cells. cDNA microarrays were used to measure changes in… CONTINUE READING


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