Stimulation by parathyroid hormone of interleukin-6 and leukemia inhibitory factor expression in osteoblasts is an immediate-early gene response induced by cAMP signal transduction.

@article{Greenfield1996StimulationBP,
  title={Stimulation by parathyroid hormone of interleukin-6 and leukemia inhibitory factor expression in osteoblasts is an immediate-early gene response induced by cAMP signal transduction.},
  author={Edward M. Greenfield and Mark C. Horowitz and S A Lavish},
  journal={The Journal of biological chemistry},
  year={1996},
  volume={271 18},
  pages={10984-9}
}
Parathyroid hormone and other agents that stimulate bone resorption function, at least in part, by inducing osteoblasts to secrete cytokines that stimulate osteoclast differentiation and activity. We previously demonstrated that parathyroid hormone induces expression by osteoblasts of interleukin-6 and leukemia inhibitory factor without affecting the 16 other cytokines that were examined. We also showed that stimulation of osteoclast activity by parathyroid hormone is dependent on activation of… CONTINUE READING

From This Paper

Figures, tables, results, connections, and topics extracted from this paper.
28 Extracted Citations
0 Extracted References
Similar Papers

Citing Papers

Publications influenced by this paper.
Showing 1-10 of 28 extracted citations

Similar Papers

Loading similar papers…