Stimulation by D-glucose of the direct conversion of arginine to citrulline in enterocytes isolated from pig jejunum.

@article{Blachier1991StimulationBD,
  title={Stimulation by D-glucose of the direct conversion of arginine to citrulline in enterocytes isolated from pig jejunum.},
  author={François Blachier and Hamida M'Rabet-Touil and B{\'e}atrice Darcy-Vrillon and Leta Posho and Pierre Henri Du{\'e}e},
  journal={Biochemical and biophysical research communications},
  year={1991},
  volume={177 3},
  pages={
          1171-7
        }
}
In enterocytes isolated from pig jejunum, L-arginine is metabolized to L-citrulline either directly or indirectly through the sequence of reactions catalysed by arginase and ornithine transcarbamylase. In the presence of 5 mM D-glucose, the direct conversion of 1mM L-[guanido-14C] arginine to L-citrulline was increased more than 4 times. Isolated enterocytes exhibit a high glycolytic capacity. Furthermore, the decarboxylation of 5mM D-[1-14C] glucose was 3.6 fold higher than the decarboxylation… CONTINUE READING
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