Stimulation and inhibition of FVIII-specific memory B-cell responses by CpG-B (ODN 1826), a ligand for Toll-like receptor 9.

@article{Allacher2011StimulationAI,
  title={Stimulation and inhibition of FVIII-specific memory B-cell responses by CpG-B (ODN 1826), a ligand for Toll-like receptor 9.},
  author={Peter Allacher and Christina K. Baumgartner and Aniko Ginta Pordes and Rafi Uddin Ahmad and Hans Peter Dr Schwarz and Birgit Maria Reipert},
  journal={Blood},
  year={2011},
  volume={117 1},
  pages={
          259-67
        }
}
Factor VIII (FVIII)-specific memory B cells are essential components for regulating anamnestic antibody responses against FVIII in hemophilia A with FVIII inhibitors. We asked how stimulation and inhibition of FVIII-specific memory B cells by low and high concentrations of FVIII, respectively, are affected by concurrent activation of the innate immune system. Using CD138(-) spleen cells from hemophilic mice treated with FVIII to study restimulation and differentiation of memory B cells in vitro… CONTINUE READING

Citations

Publications citing this paper.
SHOWING 1-10 OF 10 CITATIONS

IDO1 suppresses inhibitor development in hemophilia A treated with factor VIII.

  • The Journal of clinical investigation
  • 2015
VIEW 2 EXCERPTS
CITES BACKGROUND

References

Publications referenced by this paper.
SHOWING 1-10 OF 49 REFERENCES

Pattern recognition by Toll-like receptors.

  • Advances in experimental medicine and biology
  • 2009
VIEW 6 EXCERPTS
HIGHLY INFLUENTIAL

Approaches of enhancing immune responses stimulated with CpG oligodeoxynucleotides

G Mutwiri, LA. Babiuk
  • Adv Drug Deliv Rev
  • 2009
VIEW 5 EXCERPTS
HIGHLY INFLUENTIAL

B-cell-directed therapies for autoimmune disease

VIEW 6 EXCERPTS
HIGHLY INFLUENTIAL

Regulation and functions of Blimp-1 in T and B lymphocytes.

  • Annual review of immunology
  • 2008
VIEW 6 EXCERPTS
HIGHLY INFLUENTIAL

Similar Papers

Loading similar papers…