Stimulating regeneration in the damaged spinal cord.

  title={Stimulating regeneration in the damaged spinal cord.},
  author={John V. Priestley and Matt S. Ramer and Von R. King and Stephen B. McMahon and Robert A.M. Brown},
  journal={Journal of physiology, Paris},
  volume={96 1-2},
Great progress has been made in recent years in experimental strategies for spinal cord repair. In this review we describe two of these strategies, namely the use of neurotrophic factors to promote functional regeneration across the dorsal root entry zone (DREZ), and the use of synthetic fibronectin conduits to support directed axonal growth. The junction between the peripheral nervous system (PNS) and central nervous system (CNS) is marked by a specialized region, the DREZ, where sensory axons… CONTINUE READING