Stimulated Production of Proinflammatory Cytokines Covaries Inversely With Heart Rate Variability

@article{Marsland2007StimulatedPO,
  title={Stimulated Production of Proinflammatory Cytokines Covaries Inversely With Heart Rate Variability},
  author={Anna L. Marsland and Peter J. Gianaros and Aric A. Prather and John Richard Jennings and Serina A. Neumann and Stephen B. Manuck},
  journal={Psychosomatic Medicine},
  year={2007},
  volume={69},
  pages={709-716}
}
Objective: To examine whether high-frequency heart rate variability, an indirect measure of parasympathetic (vagal) control over variations in heart rate, is associated with immune reactivity to an in vitro inflammatory challenge. Convergent evidence from the animal literature shows that the autonomic nervous system plays a key role in regulating the magnitude of immune responses to inflammatory stimuli. Signaling by the parasympathetic system inhibits the production of proinflammatory… 
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