Still stressed out but doing fine: normalization of wall stress is superfluous to maintaining cardiac function in chronic pressure overload.

Abstract

Classically, myocardial hypertrophy is viewed as a long-term adaptive response of cardiac muscle to altered mechanical loading conditions, in which increasing wall thickness serves as the means to restore wall stress to normal, obeisant to the law of Laplace.1 The concept of local biomechanical stress as an instigator for this has been made clear through… (More)

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Cite this paper

@article{Sano2002StillSO, title={Still stressed out but doing fine: normalization of wall stress is superfluous to maintaining cardiac function in chronic pressure overload.}, author={Motoaki Sano and Michael D Schneider}, journal={Circulation}, year={2002}, volume={105 1}, pages={8-10} }