Stiffness of left ventricular cardiac fibroblasts is associated with ventricular dilation in patients with recent-onset nonischemic and nonvalvular cardiomyopathy.

@article{Glaubitz2014StiffnessOL,
  title={Stiffness of left ventricular cardiac fibroblasts is associated with ventricular dilation in patients with recent-onset nonischemic and nonvalvular cardiomyopathy.},
  author={Michael Glaubitz and Stephan Block and Jeannine Witte and Klaus Empen and Stefan Gross and Robert Schlicht and Kerstin Weitmann and Karin Klingel and Reinhard Kandolf and Wolfgang Hoffmann and Kay E Gottschalk and Mathias Busch and Marcus D{\"o}rr and Christiane A. Helm and Stephan Burkhart Felix and A. R. Riad},
  journal={Circulation journal : official journal of the Japanese Circulation Society},
  year={2014},
  volume={78 7},
  pages={1693-700}
}
BACKGROUND Ventricular dilation is known as a pivotal predictor in recent-onset cardiomyopathy (ROCM), but its pathophysiology is not fully understood. In the present study we investigated whether single-cell stiffness of right and left ventricular-derived fibroblasts has an effect on cardiac phenotype in patients with ROCM. METHODS AND RESULTS Patients… CONTINUE READING