Stiff-person syndrome following tick-borne meningoencephalitis.

  title={Stiff-person syndrome following tick-borne meningoencephalitis.},
  author={Edvard Ehler and Jan Latta and Petra Mandysov{\'a} and Jana Havlasov{\'a} and Milan Mrklovsk{\'y}},
  journal={Acta medica},
  volume={54 4},
Stiff-person syndrome (SPS) is a rare disorder characterized by muscle stiffness and painful spasms. Misdiagnosis may occur due to the fact that the clinical picture of SPS is often atypical. The main pathophysiologic mechanism underlying the development of SPS is insufficient inhibition at the cortical and spinal levels. There is good evidence for a primary autoimmune etiology. A 61-year-old man was admitted to a neurological department due to muscle hypertonia with episodic attacks of painful… CONTINUE READING
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