Sticholysins, two pore-forming toxins produced by the Caribbean Sea anemone Stichodactyla helianthus: their interaction with membranes.

@article{lvarez2009SticholysinsTP,
  title={Sticholysins, two pore-forming toxins produced by the Caribbean Sea anemone Stichodactyla helianthus: their interaction with membranes.},
  author={Carlos {\'A}lvarez and Jos{\'e} Miguel Manche{\~n}o and Diana A. Mart{\'i}nez and Mayra Tejuca and Fabiola Pazos and Mar{\'i}a E Lanio},
  journal={Toxicon : official journal of the International Society on Toxinology},
  year={2009},
  volume={54 8},
  pages={1135-47}
}
Sticholysins (Sts) I and II (StI/II) are pore-forming toxins (PFTs) produced by the Caribbean Sea anemone Stichodactyla helianthus belonging to the actinoporin family, a unique class of eukaryotic PFTs exclusively found in sea anemones. As for the rest of the members of this family, Sts are cysteine-less proteins, with molecular weights around 20 kDa, high isoelectric points (>9.5), and a preference for sphingomyelin-containing membranes. A three-dimensional structure of StII, solved by X-ray… CONTINUE READING
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Crystal

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