Stevens-Johnson syndrome and toxic epidermal necrolysis: assessment of medication risks with emphasis on recently marketed drugs. The EuroSCAR-study.

@article{Mockenhaupt2008StevensJohnsonSA,
  title={Stevens-Johnson syndrome and toxic epidermal necrolysis: assessment of medication risks with emphasis on recently marketed drugs. The EuroSCAR-study.},
  author={Maja Mockenhaupt and Cecile G. Viboud and Ariane Dunant and Luigi Naldi and Sima Halevy and J.N. Bouwes Bavinck and Alexis Sidoroff and J{\"u}rgen Schneck and Jean Claude Roujeau and Antoine Flahault},
  journal={The Journal of investigative dermatology},
  year={2008},
  volume={128 1},
  pages={
          35-44
        }
}
Stevens-Johnson syndrome (SJS) and toxic epidermal necrolysis (TEN) are rare but severe cutaneous adverse reactions (SCAR) related to a variety of medications. They have a significant public health impact because of high mortality and morbidity. A multinational case-control study conducted in Europe between 1997 and 2001 evaluated the risk of medications to induce SCAR. Cases were actively detected through a hospital network covering more than 100 million inhabitants. Three hospitalized… 
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