Stevastelin A3, D3 and E3, novel congeners from a high producing mutant of Penicillium sp.

@article{Morino1996StevastelinAD,
  title={Stevastelin A3, D3 and E3, novel congeners from a high producing mutant of Penicillium sp.},
  author={Tomio Morino and Katsuhisa Shimada and Akiko Masuda and Miyako Nishimoto and Shinichi Saito},
  journal={The Journal of antibiotics},
  year={1996},
  volume={49 10},
  pages={1049-51}
}
In our previous studies, four stevastelin congeners named A, B, B3 and C3 have been isolated from culture broth of a fungus, Penicillium, as immunosuppressants1}. Structures of these stevastelins have been elucidated to be cyclic depsipeptides2'3). In the course of ultraviolet treatment of the strain, we found that a high producing mutant yielded three novel stevastelin congeners. In this report we describe isolation, physico-chemical properties, structural elucidation and… CONTINUE READING

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