Steroids, sex and the cerebellar cortex: implications for human disease

  title={Steroids, sex and the cerebellar cortex: implications for human disease},
  author={Shannon L. Dean and Margaret M McCarthy},
  journal={The Cerebellum},
Neurosteroids play an important role in the development of the cerebellum. In particular, estradiol and progesterone appear capable of inducing increases in dendritic spine density during development, and there is evidence that both are synthesized de novo in the cerebellum during critical developmental periods. In normal neonates and adults, there are few differences in the cerebellum between the sexes and most studies indicate that hormone and receptor levels also do not differ significantly… CONTINUE READING
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