Steroidogenic factor 1 messenger ribonucleic acid expression in steroidogenic and nonsteroidogenic human tissues: Northern blot and in situ hybridization studies.

@article{Ramayya1997SteroidogenicF1,
  title={Steroidogenic factor 1 messenger ribonucleic acid expression in steroidogenic and nonsteroidogenic human tissues: Northern blot and in situ hybridization studies.},
  author={Meera S Ramayya and Jian Zhou and Tomoshige Kino and James H Segars and Carolyn A. Bondy and George P. Chrousos},
  journal={The Journal of clinical endocrinology and metabolism},
  year={1997},
  volume={82 6},
  pages={
          1799-806
        }
}
Steroidogenic factor-1 (SF-1), a tissue-specific orphan nuclear receptor, regulates the genes of several steroidogenic enzymes, Mullerian inhibiting substance, and the gonadotrophins. Also, this transcription factor is crucial for hypothalamic, adrenal, and gonadal organogenesis in the mouse. We recently cloned the human SF-1 (hSF-1) complementary DNA (cDNA) and now report the distribution of this factor's messenger RNA (mRNA) in human tissues. Northern blot analyses of peripheral tissues… CONTINUE READING
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