Steroidogenic factor-1 is an essential transcriptional activator for gonad-specific expression of promoter I of the rat prolactin receptor gene.

@article{Hu1997SteroidogenicFI,
  title={Steroidogenic factor-1 is an essential transcriptional activator for gonad-specific expression of promoter I of the rat prolactin receptor gene.},
  author={Z Z Hu and Liyan Zhuang and Xiuqin Guan and Jianping Meng and Maria L. Dufau},
  journal={The Journal of biological chemistry},
  year={1997},
  volume={272 22},
  pages={14263-71}
}
The expression of the prolactin receptor is under the control of two putative tissue-specific (PI, gonads; PII, liver) and one common (PIII) promoters (Hu, Z. Z., Zhuang, L., and Dufau, M. L. (1996) J. Biol. Chem. 271, 10242-10246). The three promoter regions were co-localized to the rat chromosomal locus 2ql6, in the order 5'-PIII-PI-PII-3'. To investigate the mechanisms of gonad-specific utilization of PI, the promoter domain, regulatory cis-elements, and trans-factors were identified in… CONTINUE READING

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Prolactin Receptor Promoter I

S. Osada, H. Yamamoto, T. Nishihara, M. Imagawa
J. Biol. Chem • 1996

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