Steroidogenic electron transport in adrenal cortex mitochondria

  title={Steroidogenic electron transport in adrenal cortex mitochondria},
  author={J. David Lambeth and David W. Seybert and Jack R. Lancaster and John C. Salerno and Henry Kamin},
  journal={Molecular and Cellular Biochemistry},
The flavoprotein NADPH-adrenodoxin reductase and the iron sulfur protein adrenodoxin function as a short electron transport chain which donates electrons one-at-a-time to adrenal cortex mitochondrial cytochromes P-450. The soluble adrenodoxin acts as a mobile one-electron shuttle, forming a complex first with NADPH-reduced adrenodoxin reductase from which it accepts an electron, then dissociating, and finally reassociating with and donating an electron to the membrane-bound cytochrome P-450… CONTINUE READING
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In Flavins and Flavopro- teins (Yagi, K

  • J. D. Lambeth, H. Kamin
  • 1980

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