Steroidal Compounds in Commercial Parenteral Lipid Emulsions

  title={Steroidal Compounds in Commercial Parenteral Lipid Emulsions},
  author={Zhidong Xu and Kevin A. Harvey and Thomas M. Pavlina and Guy Dutot and Mary Hise and Gary P. Zaloga and Rafat A. Siddiqui},
Parenteral nutrition lipid emulsions made from various plant oils contain steroidal compounds, called phytosterols. During parenteral administration of lipid emulsions, phytosterols can reach levels in the blood that are many fold higher than during enteral administration. The elevated phytosterol levels have been associated with the development of liver dysfunction and the rare development of liver failure. There is limited information available in the literature related to phytosterol… CONTINUE READING
Related Discussions
This paper has been referenced on Twitter 2 times. VIEW TWEETS


Publications citing this paper.
Showing 1-10 of 16 extracted citations

Phytosterol determination in lipid emulsions for parenteral nutrition.

Farmacia hospitalaria : organo oficial de expresion cientifica de la Sociedad Espanola de Farmacia Hospitalaria • 2018


Publications referenced by this paper.
Showing 1-10 of 61 references

Preventing parenteral nutrition liver disease.

Early human development • 2010
View 9 Excerpts
Highly Influenced

Prevention of parenteral nutrition-associated liver disease: lipid minimization.

Current opinion in organ transplantation • 2010
View 10 Excerpts
Highly Influenced

Effect of parenteral serum plant sterols on liver enzymes and cholesterol metabolism in a patient with short bowel syndrome.

Nutrition in clinical practice : official publication of the American Society for Parenteral and Enteral Nutrition • 2008
View 4 Excerpts
Highly Influenced

Managing liver dysfunction in parenteral nutrition.

The Proceedings of the Nutrition Society • 2007
View 8 Excerpts
Highly Influenced

Squalene: Current Knowledge and Potential Therapeutic Uses; Nova Biomedical Books

A. Ramirez-Torres, C. Gabas, C. Barranquero
View 2 Excerpts

Similar Papers

Loading similar papers…