Steroid use in Lyme disease‐associated facial palsy is associated with worse long‐term outcomes

  title={Steroid use in Lyme disease‐associated facial palsy is associated with worse long‐term outcomes},
  author={Nate Jowett and Robert A. Gaudin and Caroline A. Banks and Tessa A. Hadlock},
  journal={The Laryngoscope},
OBJECTIVE The purpose of this study was to determine whether differences in long-term facial function outcomes following acute Lyme disease-associated facial palsy (LDFP) exist between patients who received antibiotic monotherapy (MT); dual therapy (DT) with antibiotics and corticosteroids; and triple therapy (TT) with antibiotics, corticosteroids, and antivirals. [] Key MethodSTUDY DESIGN Retrospective cohort.

Characteristics and outcome of facial nerve palsy from Lyme neuroborreliosis in the United States

This study aimed to describe features of patients with early LNB presenting with facial palsy and to determine if corticosteroids in addition to antibiotic therapy was associated with unfavorable outcome.

Lyme Disease with Erythema Migrans and Seventh Nerve Palsy in an African-American Man

An African-American man in his 30s presented following seven weeks of symptoms including an initial febrile illness with a rash followed by onset of fatigue, facial weakness, daily headaches, neck pain, leg numbness, hyperacusis, and photosensitivity, and he was diagnosed with post-treatment Lyme disease syndrome (PTLDS).

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The use of steroids and antivirals in the setting of idiopathic facial paralysis or virus-associated facial paralysis is well supported and there is a lack of consensus regarding optimal treatment.

Differentiating Bell's Palsy From Lyme-Related Facial Palsy.

Bell's palsy and LRFP were common causes of pediatric FP in the authors' Lyme endemic region and early corticosteroid use did not impact measures of recovery, although subtle abnormalities may not have been appreciated, and time to recovery could not be assessed.

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Onset of bell's palsy in late pregnancy and early puerperium is associated with worse long‐term outcomes

The incidence of Bell's palsy (BP) is elevated in the late phases of pregnancy. Controversy exists as to whether pregnancy is a risk factor for worse outcomes in BP, and whether such outcomes are the

Infectious causes of peripheral facial nerve palsy in children—a retrospective cohort study with long-term follow-up

Long-term follow-up revealed an associated lower risk of relapse in CNS infection–associated pFP, and permanent sequelae were associated with female sex, a shorter length of hospitalization, and a lower white blood cell count at presentation.

A rare case of pseudotumor cerebri in adult Lyme disease

An adult case of chronic Lyme disease is presented, who developed pseudotumor cerebri and who needed supplementary surgical treatment, and is compared to the existing published literature, reviewed by a systematic approach.



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The overall current health status of each patient group was good, but sequelae were apparent primarily among patients with facial palsy who did not receive antibiotics for acute neuroborreliosis.

Perineuritis in acute lyme neuroborreliosis

This study supports the notion that perineuritis forms part of the pathogenesis in acute Lyme neuroborreliosis and treatment with intravenous ceftriaxone resulted in marked neurologic improvement.

Histopathology of bell's palsy

The histopathology of the facial nerve 1 week after the onset of Bell's palsy suggests viral neuritis, and the role of decompression in this disease process is discussed.

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AAEM case report #26: Seventh cranial neuropathy

The clinical course was consistent with these findings as the right side fully recovered and the left remained plegic and the electrodiagnostic evaluation of facial palsy.

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In Bell palsy, corticosteroids are associated with a reduced risk of unsatisfactory recovery and antiviral agents, when administered with cortiosteroids, may be associated with additional benefit.

Bell’s palsy during etanercept treatment caused by neuroborreliosis

This case report is the first description of an unusual lung involvement in the course of a colon cancer-related DM, associating initial DAH with a classical ILD leading to a residual asymptomatic pulmonary fibrosis.

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A contemporary approach to the management of facial nerve insults is summarized, which aims to restore facial balance and movement in patients with long-standing facial palsy.

Facial Paralysis from Lyme Disease

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This single case does not resolve the matter, since the ponenrs vestibular problem could have arisen from Infection or even spontaneously, but it would seem wise to avoid long-term use of amlnoglycoslde drops through a dry perforation, as used In the reported case.

Lyme borreliosis in Bell's palsy. Long Island Neuroborreliosis Collaborative Study Group.

Rarely, the palsy may occur prior to the development of a measurable antibody response, indicating a need for follow-up serologic testing.