Steroid synthesis in ovarian homogenates from hypophysectomized adult female mice treated with diethylstilbestrol in neonatal life.

@article{Halling1992SteroidSI,
  title={Steroid synthesis in ovarian homogenates from hypophysectomized adult female mice treated with diethylstilbestrol in neonatal life.},
  author={Anneliis Halling},
  journal={Journal of toxicology and environmental health},
  year={1992},
  volume={36 4},
  pages={341-53}
}
  • Anneliis Halling
  • Published 1992 in Journal of toxicology and environmental health
Eight-week-old female NMRI-mice treated with 5 micrograms diethylstilbestrol (DES) or vehicle (olive oil) from d 1 to 5 after birth were hypophysectomized or sham operated. Thirty days after the operation, homogenates were prepared from the ovaries and incubated at 37 degrees C in the presence of [3H]pregnenolone for 1 h. In parallel experiments ovaries… CONTINUE READING