Steroid sulfation Current concepts.

  title={Steroid sulfation Current concepts.},
  author={R. Hobkirk},
  journal={Trends in endocrinology and metabolism: TEM},
  volume={4 2},
  • R. Hobkirk
  • Published 1993 in Trends in endocrinology and metabolism: TEM
Formation of steroid sulfates is catalyzed by sulfotransferase enzymes that are widely distributed and frequently of high specificity. Steroid sulfates cannot be described as being active hormones, but some serve in tissue sites as precursors of active steroids formed by enzymic cleavage of the sulfate group by sulfatase enzymes. There is increasing evidence that intracellular sulfation and desulfation can play a role in regulating the availability of active steroid hormones near target sites… CONTINUE READING

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